October 5, 2020 - Monday
The last few days have left me feeling like, I imagine, a sea bird in an oil spill. The weekend has been the emotional equivalent of the Exxon Valdez or Deepwater Horizon - a preventable spill of something crude that you cannot ignore. There are so many consequences emanating from the President getting sick. His profound recklessness ripples - as both a source of contagion and as a bad example for others. It is hard to muster sympathy. Perhaps the most appropriate word is sullen - anger at yet another flair of acute on chronic sadness. None of this had to be this way.
-----Latest Data---
Stable as of the end of last week:
40,000 New cases per day (7-day rolling average) in the U.S.
Declining still:
600-700 new deaths per day (7-day rolling average) in the U.S.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=cases
Also, look at https://covidtracking.com/data
The U.S. Regionally:
The NY Times state-level data visualization:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
----
The COVIDtracking.com blog's October 1 update was an excellent analysis of trends from last week. The final few paragraphs highlight the mix of news - in aggregate, COVID is better controlled than it was, but there are continued troubling regional trends. And, when looking at the actual numbers, way too many cases and deaths.
https://covidtracking.com/blog/good-news-big-picture-regional-weekly-more-troubling-this-week-in-covid-19-data-oct-1
Twitter has yielded quite a review of COVID therapy this weekend, largely thanks to the deductive reasoning imputing the magnitude of Presidential illness. Here are a few examples:
Let's start with Eric Topol's review of the data about Regeneron's monoclonal antibody cocktail. https://twitter.com/EricTopol/status/1312816650987565056
Dr. Eric Feigl-Ding offers a review of the U.K. data on dexamethasone use. Data only indicates an improvement in patients requiring supplemental oxygen.
https://twitter.com/drericding/status/1312813423185584128?s=10
Lastly, I am still intrigued by the data on the antacid, Famotidine. There was a reasonable retrospective study a few months back.
https://twitter.com/amjgastro/status/1312412910807904257?s=10
The Financial Times offered this piece on China's expansion of a COVID vaccine before completing Phase 3 trials. I think the question is, how prepared are they for unintended consequences?
https://www.ft.com/content/6a7289e6-45a5-410d-98c0-9977e4026af1
Infographic of the day - Amino Acid Etymology
https://twitter.com/etymology_nerd/status/1310560462329831425/photo/1
I did not know Asapargus juice was a thing before the juicing rage of the 1970s. Asparagine has taught me otherwise! Thank you to Pierre Jean Robiquet - https://www.sciencedirect.com/science/article/pii/S0187893X13725072
Oddly, the 1970's "father of juicing" was also from France,
https://www.theatlantic.com/health/archive/2014/11/the-man-who-first-juiced/382586/
----Bonus Round - Snack foods Edition
I recently found this interesting article from 2006 on Proctor and Gamble's use of AI (more of an automated iterative design process) to optimize the shape of Pringles for aerodynamics in high-speed manufacturing.
https://www.hpcwire.com/2006/05/05/high_performance_potato_chips/
There are, it turns out, numerous articles on the form as well:
https://interestingengineering.com/geometry-of-pringles-crunchy-hyperbolic-paraboloid
In a similar exploration of snack food ephemera, Dr. Cooper, an ICU doc and "tweetorialist," offers an overview of Brain Freeze physiology. AKA, acute cerebral vasodilation due to cold temperatures stimulation of the sphenopalatine ganglion. There are numerous studies with data on this phenomenon. Amazing.
https://twitter.com/AvrahamCooperMD/status/1312392275880804353
Clean hands and sharp minds, team
-Adam
The last few days have left me feeling like, I imagine, a sea bird in an oil spill. The weekend has been the emotional equivalent of the Exxon Valdez or Deepwater Horizon - a preventable spill of something crude that you cannot ignore. There are so many consequences emanating from the President getting sick. His profound recklessness ripples - as both a source of contagion and as a bad example for others. It is hard to muster sympathy. Perhaps the most appropriate word is sullen - anger at yet another flair of acute on chronic sadness. None of this had to be this way.
-----Latest Data---
Stable as of the end of last week:
40,000 New cases per day (7-day rolling average) in the U.S.
Declining still:
600-700 new deaths per day (7-day rolling average) in the U.S.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=cases
Also, look at https://covidtracking.com/data
The U.S. Regionally:
The NY Times state-level data visualization:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
----
The COVIDtracking.com blog's October 1 update was an excellent analysis of trends from last week. The final few paragraphs highlight the mix of news - in aggregate, COVID is better controlled than it was, but there are continued troubling regional trends. And, when looking at the actual numbers, way too many cases and deaths.
https://covidtracking.com/blog/good-news-big-picture-regional-weekly-more-troubling-this-week-in-covid-19-data-oct-1
Twitter has yielded quite a review of COVID therapy this weekend, largely thanks to the deductive reasoning imputing the magnitude of Presidential illness. Here are a few examples:
Let's start with Eric Topol's review of the data about Regeneron's monoclonal antibody cocktail. https://twitter.com/EricTopol/status/1312816650987565056
Dr. Eric Feigl-Ding offers a review of the U.K. data on dexamethasone use. Data only indicates an improvement in patients requiring supplemental oxygen.
https://twitter.com/drericding/status/1312813423185584128?s=10
Lastly, I am still intrigued by the data on the antacid, Famotidine. There was a reasonable retrospective study a few months back.
https://twitter.com/amjgastro/status/1312412910807904257?s=10
The Financial Times offered this piece on China's expansion of a COVID vaccine before completing Phase 3 trials. I think the question is, how prepared are they for unintended consequences?
https://www.ft.com/content/6a7289e6-45a5-410d-98c0-9977e4026af1
Infographic of the day - Amino Acid Etymology
https://twitter.com/etymology_nerd/status/1310560462329831425/photo/1
I did not know Asapargus juice was a thing before the juicing rage of the 1970s. Asparagine has taught me otherwise! Thank you to Pierre Jean Robiquet - https://www.sciencedirect.com/science/article/pii/S0187893X13725072
Oddly, the 1970's "father of juicing" was also from France,
https://www.theatlantic.com/health/archive/2014/11/the-man-who-first-juiced/382586/
----Bonus Round - Snack foods Edition
I recently found this interesting article from 2006 on Proctor and Gamble's use of AI (more of an automated iterative design process) to optimize the shape of Pringles for aerodynamics in high-speed manufacturing.
https://www.hpcwire.com/2006/05/05/high_performance_potato_chips/
There are, it turns out, numerous articles on the form as well:
https://interestingengineering.com/geometry-of-pringles-crunchy-hyperbolic-paraboloid
In a similar exploration of snack food ephemera, Dr. Cooper, an ICU doc and "tweetorialist," offers an overview of Brain Freeze physiology. AKA, acute cerebral vasodilation due to cold temperatures stimulation of the sphenopalatine ganglion. There are numerous studies with data on this phenomenon. Amazing.
https://twitter.com/AvrahamCooperMD/status/1312392275880804353
Clean hands and sharp minds, team
-Adam
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