Thursday, January 21, 2021
I slept pretty well last night. I hope you did too.
-----Latest Data---
New cases are decreasing on the F.T. charts for the U.S. and the U.K.
The U.S. average went up to ~900,000 vaccine doses per day yesterday.
All data above is reflective of 7-day rolling averages.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
Also, look at https://covidtracking.com/data
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
Vaccine Tracker
https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/
-----
I found a discussion about this article on droplet clouds (slipstream aerosols) emitted by runners and others engaged in outdoor exercise. Given the new strains, with increased transmissibility, making their way through the population, I think it is worth wearing a mask outdoors if around those running/jogging. The downside of discomfort seems a small trade-off in diminishing exposure, especially in light of the incomplete understanding of what is "best."
https://twitter.com/kamleshkhunti/status/1352180108312915970
Here is another article on the topic "In this nationwide survey of U.S. high school athletic directors representing 152,484 athletes, lower COVID-19 incidence was independently associated with participation in outdoor versus indoor and non-contact versus contact sports, but not team versus individual sports. Face mask use was associated with decreased COVID-19 incidence among indoor sports, and may be protective among outdoor sports with prolonged close contact between participants."
https://www.medrxiv.org/content/10.1101/2021.01.19.21250116v1?rss=1%22
Immunologist Vinci Wang offered a detailed and well-documented summary of his lab's work comparing vaccine-induced antibody response to post-infectious antibody response. The bottom line, their data suggest vaccine-induced immunity is as good as natural immunity. But, both natural and vaccine-induced antibodies are less effective (in vitro) against new strains. However, both the monoclonal antibodies and the vaccines will need to be updated in time to accommodate an evolving virus.
https://twitter.com/VinciZijun/status/1351707342061129729
A loyal reader shared a link to similar data out of Cambridge. "There is a modest reduction in the efficacy of vaccine sera [to B1.1.17]"
https://twitter.com/GuptaR_lab/status/1351181780804636675
And here is an article about weak science driving decisions about the coronavirus response. School boards are one of those opportunities to participate in civic life, by the way.
https://www.realclearscience.com/blog/2021/01/18/schools_are_installing_a_game_changer_filtration_system_to_fight_the_coronavirus_theres_no_good_evidence_it_works_656837.html
Meet our COVID fixer in Chief. Day 1, today, is going to be tough.
https://www.ft.com/content/b52ca23e-d244-498b-8199-5f7bd3f64177
Infographic of the day: The Heads of Heads of State, (Disembodied Floating Edition)
https://www.visualcapitalist.com/visualized-world-leaders-in-positions-of-power/
While the overlapping timeline is reasonable, not sure how I feel about the floating head bit. Facial expressions are telling, perhaps?
---Bonus Round - The Righteous Indignation Vacuum
There is a trope in the superhero genre about how the hero without the villain is lost. Their raison d'être has vanished. To be sure, my diet of incessant media ingestion felt a little less purposeful after 12:01 EST yesterday. Fortunately(?) the world offers numerous topics about which to be outraged. We should probably start small, though.
As such, I offer a small story from recent history: Sigmund Freud's grandson Lucian. He was a world-famous, nasty, philandering painter. His artistic skill seemed to be his most redeeming attribute. There is so much irony in this story. He feels like a less-violent Bond villain celebrated for his work.
https://www.nytimes.com/2021/01/18/books/review-lives-lucian-freud-fame-william-feaver.html
Clean hands and sharp minds,
-Adam
Back in clinic tomorrow, more on Monday
I slept pretty well last night. I hope you did too.
-----Latest Data---
New cases are decreasing on the F.T. charts for the U.S. and the U.K.
The U.S. average went up to ~900,000 vaccine doses per day yesterday.
All data above is reflective of 7-day rolling averages.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
Also, look at https://covidtracking.com/data
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
Vaccine Tracker
https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/
-----
I found a discussion about this article on droplet clouds (slipstream aerosols) emitted by runners and others engaged in outdoor exercise. Given the new strains, with increased transmissibility, making their way through the population, I think it is worth wearing a mask outdoors if around those running/jogging. The downside of discomfort seems a small trade-off in diminishing exposure, especially in light of the incomplete understanding of what is "best."
https://twitter.com/kamleshkhunti/status/1352180108312915970
Here is another article on the topic "In this nationwide survey of U.S. high school athletic directors representing 152,484 athletes, lower COVID-19 incidence was independently associated with participation in outdoor versus indoor and non-contact versus contact sports, but not team versus individual sports. Face mask use was associated with decreased COVID-19 incidence among indoor sports, and may be protective among outdoor sports with prolonged close contact between participants."
https://www.medrxiv.org/content/10.1101/2021.01.19.21250116v1?rss=1%22
Immunologist Vinci Wang offered a detailed and well-documented summary of his lab's work comparing vaccine-induced antibody response to post-infectious antibody response. The bottom line, their data suggest vaccine-induced immunity is as good as natural immunity. But, both natural and vaccine-induced antibodies are less effective (in vitro) against new strains. However, both the monoclonal antibodies and the vaccines will need to be updated in time to accommodate an evolving virus.
https://twitter.com/VinciZijun/status/1351707342061129729
A loyal reader shared a link to similar data out of Cambridge. "There is a modest reduction in the efficacy of vaccine sera [to B1.1.17]"
https://twitter.com/GuptaR_lab/status/1351181780804636675
And here is an article about weak science driving decisions about the coronavirus response. School boards are one of those opportunities to participate in civic life, by the way.
https://www.realclearscience.com/blog/2021/01/18/schools_are_installing_a_game_changer_filtration_system_to_fight_the_coronavirus_theres_no_good_evidence_it_works_656837.html
Meet our COVID fixer in Chief. Day 1, today, is going to be tough.
https://www.ft.com/content/b52ca23e-d244-498b-8199-5f7bd3f64177
Infographic of the day: The Heads of Heads of State, (Disembodied Floating Edition)
https://www.visualcapitalist.com/visualized-world-leaders-in-positions-of-power/
While the overlapping timeline is reasonable, not sure how I feel about the floating head bit. Facial expressions are telling, perhaps?
---Bonus Round - The Righteous Indignation Vacuum
There is a trope in the superhero genre about how the hero without the villain is lost. Their raison d'être has vanished. To be sure, my diet of incessant media ingestion felt a little less purposeful after 12:01 EST yesterday. Fortunately(?) the world offers numerous topics about which to be outraged. We should probably start small, though.
As such, I offer a small story from recent history: Sigmund Freud's grandson Lucian. He was a world-famous, nasty, philandering painter. His artistic skill seemed to be his most redeeming attribute. There is so much irony in this story. He feels like a less-violent Bond villain celebrated for his work.
https://www.nytimes.com/2021/01/18/books/review-lives-lucian-freud-fame-william-feaver.html
Clean hands and sharp minds,
-Adam
Back in clinic tomorrow, more on Monday
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