Wednesday, January 27, 2021
Despite 12+ hours of meetings and calls, I took the most satisfaction from repairing a fake tree residing in our dining room yesterday. Suspending the broken branches with string, small clamps, and clear glue into biologically plausible angles was quite fulfilling. Our fake tree is whole again and looks no less artificial than it did. At the risk of bragging, there is an almost wabi-sabi-like beauty to the repair. Oddly, I think the tree and I bonded through our mutual history of imperfection. Or perhaps I projected all this into the void of moments I couldn't use my phone due to holding branches and waiting for glue to dry.
-----Latest Data---
No change in patterns of new cases or deaths.
The U.S. average went up to ~1,270,000 vaccine doses per day yesterday.
All data above is reflective of 7-day rolling averages.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
Also, look at https://covidtracking.com/data
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
Vaccine Tracker
https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/
-----
Carl Bergstrom, Biology Professor from the University of Washington, shared thoughts from a recent paper he published on modeling the impact of mitigation strategies for reopening schools. It is complex probability calculations. His group made numerous assumptions to complete the work. But, the discussion is an excellent window into how thoughtful professionals model complex problems. I suggest you read through the comments at the bottom of the thread as well.
https://twitter.com/CT_Bergstrom/status/1354082203098095617
This article on CDC recommendations regarding school reopening is a good follow-on.
https://www.washingtonpost.com/education/cdc-school-virus-spread/2021/01/26/bf949222-5fe6-11eb-9061-07abcc1f9229_story.html
John Burn-Murdoch (the visualization guy from FT) offered a very comprehensive view of the data on COVID-19 deaths vs. other causes of death in the U.K. He discusses how mortality is calculated and attributed despite changing societal patterns (like staying home and wearing masks). https://twitter.com/jburnmurdoch/status/1354158365778333696
It is a little old at this point, but this MMWR report is a good reminder of how few genuine anaphylactic reactions to the Pfizer vaccine have been documented. "During December 14–23, 2020, monitoring by the Vaccine Adverse Event Reporting System detected 21 cases of anaphylaxis after administration of a reported 1,893,360 first doses of the Pfizer-BioNTech COVID-19 vaccine (11.1 cases per million doses); 71% of these occurred within 15 minutes of vaccination."
https://www.cdc.gov/mmwr/volumes/70/wr/mm7002e1.htm
There are more efforts at using monoclonal antibodies for early COVID patients and, now, post-exposure prophylaxis. Dr. Boulware, an ID doc from Minnesota, discussed the interim data from an ongoing trial of subcutaneous injections of Regeneron MAb as a passive vaccine. The data is intriguing but not definitive.
https://www.prnewswire.com/news-releases/regeneron-reports-positive-interim-data-with-regen-cov-antibody-cocktail-used-as-passive-vaccine-to-prevent-covid-19-301214619.html
and
https://twitter.com/boulware_dr/status/1354059455672016898
Infographic of the day: Baseball Proposals
I was surprised to learn you have to pay to propose marriage at baseball stadiums.
https://www.bridalguide.com/blogs/how-much-it-costs-propose-each-mlb-stadium
-----Bonus Round - Ancient Fast Food
I have had the fortune to visit Pompeii twice. Both times, the remnants of the buffet counters in pubs were quite striking - there a quite a few, and they are profoundly recognizable, despite being 2000 years old. Some recent archeology discoveries have brought one of the eateries back into the news. It seems like "broth and chunks of meat" is something that links homo sapiens across millennia. Moreover, it seems that solving for feeding a crowd has a finite number of solutions. Here is an article about Roman-style pub food.
https://www.atlasobscura.com/articles/recreate-the-menu-of-pompeii-ancient-pub
Clean hands and sharp minds, team
Adam
I'll be getting the second dose of the Moderna vaccine later today. I can only assume I will be even taller, better looking, and wittier as a result (more so than after the first dose). Be prepared for the full report.
Despite 12+ hours of meetings and calls, I took the most satisfaction from repairing a fake tree residing in our dining room yesterday. Suspending the broken branches with string, small clamps, and clear glue into biologically plausible angles was quite fulfilling. Our fake tree is whole again and looks no less artificial than it did. At the risk of bragging, there is an almost wabi-sabi-like beauty to the repair. Oddly, I think the tree and I bonded through our mutual history of imperfection. Or perhaps I projected all this into the void of moments I couldn't use my phone due to holding branches and waiting for glue to dry.
-----Latest Data---
No change in patterns of new cases or deaths.
The U.S. average went up to ~1,270,000 vaccine doses per day yesterday.
All data above is reflective of 7-day rolling averages.
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
Also, look at https://covidtracking.com/data
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
About the data:
https://covidtracking.com/about-data/visualization-guide is the best resource to understand data visualization and data integrity.
Vaccine Tracker
https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/
-----
Carl Bergstrom, Biology Professor from the University of Washington, shared thoughts from a recent paper he published on modeling the impact of mitigation strategies for reopening schools. It is complex probability calculations. His group made numerous assumptions to complete the work. But, the discussion is an excellent window into how thoughtful professionals model complex problems. I suggest you read through the comments at the bottom of the thread as well.
https://twitter.com/CT_Bergstrom/status/1354082203098095617
This article on CDC recommendations regarding school reopening is a good follow-on.
https://www.washingtonpost.com/education/cdc-school-virus-spread/2021/01/26/bf949222-5fe6-11eb-9061-07abcc1f9229_story.html
John Burn-Murdoch (the visualization guy from FT) offered a very comprehensive view of the data on COVID-19 deaths vs. other causes of death in the U.K. He discusses how mortality is calculated and attributed despite changing societal patterns (like staying home and wearing masks). https://twitter.com/jburnmurdoch/status/1354158365778333696
It is a little old at this point, but this MMWR report is a good reminder of how few genuine anaphylactic reactions to the Pfizer vaccine have been documented. "During December 14–23, 2020, monitoring by the Vaccine Adverse Event Reporting System detected 21 cases of anaphylaxis after administration of a reported 1,893,360 first doses of the Pfizer-BioNTech COVID-19 vaccine (11.1 cases per million doses); 71% of these occurred within 15 minutes of vaccination."
https://www.cdc.gov/mmwr/volumes/70/wr/mm7002e1.htm
There are more efforts at using monoclonal antibodies for early COVID patients and, now, post-exposure prophylaxis. Dr. Boulware, an ID doc from Minnesota, discussed the interim data from an ongoing trial of subcutaneous injections of Regeneron MAb as a passive vaccine. The data is intriguing but not definitive.
https://www.prnewswire.com/news-releases/regeneron-reports-positive-interim-data-with-regen-cov-antibody-cocktail-used-as-passive-vaccine-to-prevent-covid-19-301214619.html
and
https://twitter.com/boulware_dr/status/1354059455672016898
Infographic of the day: Baseball Proposals
I was surprised to learn you have to pay to propose marriage at baseball stadiums.
https://www.bridalguide.com/blogs/how-much-it-costs-propose-each-mlb-stadium
-----Bonus Round - Ancient Fast Food
I have had the fortune to visit Pompeii twice. Both times, the remnants of the buffet counters in pubs were quite striking - there a quite a few, and they are profoundly recognizable, despite being 2000 years old. Some recent archeology discoveries have brought one of the eateries back into the news. It seems like "broth and chunks of meat" is something that links homo sapiens across millennia. Moreover, it seems that solving for feeding a crowd has a finite number of solutions. Here is an article about Roman-style pub food.
https://www.atlasobscura.com/articles/recreate-the-menu-of-pompeii-ancient-pub
Clean hands and sharp minds, team
Adam
I'll be getting the second dose of the Moderna vaccine later today. I can only assume I will be even taller, better looking, and wittier as a result (more so than after the first dose). Be prepared for the full report.
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