Monday, May 3, 2021
Over the weekend, we had two hours' notice that we were hosting a small family gathering on our patio (an urgent venue change). Despite a year of limited social events, we have retained the capacity for party mode at our house - with martial precision and unplanned deployment. And even though this was a group of vaccinated adults (in an outdoor space), the affair felt a bit surreal and clandestine. I look forward to no longer feeling the need to qualify the size, outdoor status, and vaccination status of events at my house.
---
CDC National Hospitalization trend data
https://covid.cdc.gov/covid-data-tracker/#hospitalizations
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
Vaccine Tracker
https://covid.cdc.gov/covid-data-tracker/#vaccination-trends
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The CDC's May 1st weekly review highlights thoughts on summer travel, amongst a variety of data indicating improvements, at the national level, over the last 7-10 days. I am concerned about this data, "Overall, about 143.7 million people, or 43.3% of the total U.S. population, have received at least one dose of vaccine. As of last week, about 99.7 million people, or 30% of the total U.S. population, have been fully vaccinated." Vaccination rates need to go higher.
https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/index.html
see
https://twitter.com/erictopol/status/1388509328185782277?s=10
Eric Topol highlighted some comforting data about how well the vaccines are protecting against the variants.
https://twitter.com/erictopol/status/1388916930988240898?s=10
Carl Bergstrom offered some related math based on the Israeli experience with the B.1.617 strain.
https://twitter.com/CT_Bergstrom/status/1387941641395179524?s=20
Individuals who have already been infected with coronavirus and receive at least one vaccine dose have a more robust T-cell response than those receiving two vaccine doses with no prior infection. This data is a solid argument reinforcing the need to vaccinate previously infected individuals.
Article
https://science.sciencemag.org/content/early/2021/04/29/science.abh1282
Commentary
https://twitter.com/EricTopol/status/1388137563332874242?s=20
I'll repeat this: this pandemic will shape entire careers. Here is bench-top research looking at the pathophysiology of exposure to the coronavirus spike protein. By itself, the spike protein causes cellular damage by disrupting intracellular communication pathways. What are those pathways? What happens when we build a variety of molecules to differentially bind, block, or activate the same receptors or downstream signaling? This data raises so many questions worthy of exploration.
https://scitechdaily.com/covid-19-is-a-vascular-disease-coronavirus-spike-protein-attacks-vascular-system-on-a-cellular-level/
Article
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902
Infographics of the day: Shoes!
I am not sure when in life I was supposed to learn all this. I am still not sure I could distinguish "peep toe" from "pump" and "platform."
https://www.bows-n-ties.com/mens-fashion-tips/wp-content/uploads/2015/11/Shoe_Guide.jpg
and
http://alldaychic.com/wp-content/uploads/2014/01/encyclopedia-of-womans-shoes-or-visual-shoe-dictionary.jpg
-----Bonus Round - Two follow up items - inflight Yiddish and talking dogs
In my poking around for articles on the aerospace industry last week, I came upon this delightful article on the derivation of the word Glitch. It turns out it started as glitsh (a slippery place), which is the noun form of glitshn (to slide). Add John Glenn and NASA for mass socialization.
https://www.airspacemag.com/airspacemag/just-right-word-180973113/
I also discovered Stella, the talking dog, over the weekend. It appears you can train a dog to communicate in English. It helps if you are a speech therapist.
https://www.youtube.com/watch?v=MTHktun5vKc
https://www.hungerforwords.com/
Clean hands and sharp minds,
Adam
Over the weekend, we had two hours' notice that we were hosting a small family gathering on our patio (an urgent venue change). Despite a year of limited social events, we have retained the capacity for party mode at our house - with martial precision and unplanned deployment. And even though this was a group of vaccinated adults (in an outdoor space), the affair felt a bit surreal and clandestine. I look forward to no longer feeling the need to qualify the size, outdoor status, and vaccination status of events at my house.
---
CDC National Hospitalization trend data
https://covid.cdc.gov/covid-data-tracker/#hospitalizations
Global-View:
https://www.ft.com/content/a2901ce8-5eb7-4633-b89c-cbdf5b386938
Nationally:
https://ig.ft.com/coronavirus-chart/?areas=usa&areas=gbr&areasRegional=usny&areasRegional=usca&areasRegional=usfl&areasRegional=ustx&areasRegional=usco&cumulative=0&logScale=0&perMillion=1&values=casesf
The U.S. Regionally - N.Y. Times:
https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
Vaccine Tracker
https://covid.cdc.gov/covid-data-tracker/#vaccination-trends
-----
The CDC's May 1st weekly review highlights thoughts on summer travel, amongst a variety of data indicating improvements, at the national level, over the last 7-10 days. I am concerned about this data, "Overall, about 143.7 million people, or 43.3% of the total U.S. population, have received at least one dose of vaccine. As of last week, about 99.7 million people, or 30% of the total U.S. population, have been fully vaccinated." Vaccination rates need to go higher.
https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/index.html
see
https://twitter.com/erictopol/status/1388509328185782277?s=10
Eric Topol highlighted some comforting data about how well the vaccines are protecting against the variants.
https://twitter.com/erictopol/status/1388916930988240898?s=10
Carl Bergstrom offered some related math based on the Israeli experience with the B.1.617 strain.
https://twitter.com/CT_Bergstrom/status/1387941641395179524?s=20
Individuals who have already been infected with coronavirus and receive at least one vaccine dose have a more robust T-cell response than those receiving two vaccine doses with no prior infection. This data is a solid argument reinforcing the need to vaccinate previously infected individuals.
Article
https://science.sciencemag.org/content/early/2021/04/29/science.abh1282
Commentary
https://twitter.com/EricTopol/status/1388137563332874242?s=20
I'll repeat this: this pandemic will shape entire careers. Here is bench-top research looking at the pathophysiology of exposure to the coronavirus spike protein. By itself, the spike protein causes cellular damage by disrupting intracellular communication pathways. What are those pathways? What happens when we build a variety of molecules to differentially bind, block, or activate the same receptors or downstream signaling? This data raises so many questions worthy of exploration.
https://scitechdaily.com/covid-19-is-a-vascular-disease-coronavirus-spike-protein-attacks-vascular-system-on-a-cellular-level/
Article
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902
Infographics of the day: Shoes!
I am not sure when in life I was supposed to learn all this. I am still not sure I could distinguish "peep toe" from "pump" and "platform."
https://www.bows-n-ties.com/mens-fashion-tips/wp-content/uploads/2015/11/Shoe_Guide.jpg
and
http://alldaychic.com/wp-content/uploads/2014/01/encyclopedia-of-womans-shoes-or-visual-shoe-dictionary.jpg
-----Bonus Round - Two follow up items - inflight Yiddish and talking dogs
In my poking around for articles on the aerospace industry last week, I came upon this delightful article on the derivation of the word Glitch. It turns out it started as glitsh (a slippery place), which is the noun form of glitshn (to slide). Add John Glenn and NASA for mass socialization.
https://www.airspacemag.com/airspacemag/just-right-word-180973113/
I also discovered Stella, the talking dog, over the weekend. It appears you can train a dog to communicate in English. It helps if you are a speech therapist.
https://www.youtube.com/watch?v=MTHktun5vKc
https://www.hungerforwords.com/
Clean hands and sharp minds,
Adam
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